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… of secondary metabolism. Welcome back. This will be episode 12 of Natural Prodcast. And it’s our conversation with … Europe. So if there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And …

… metabolism. Hey everybody, this is Dan with episode 13 of National Prodcast. This continues our little section … and I hope you’ll enjoy it too. So here we go– episode 13 with Paco Barona-Goméz. DAN UDWARY: Hey Alison. ALISON …

… like a nice summer day in Seattle I think this was like 2013 or 2014. And antiSMASH — I know you’ve interviewed Marnix … access to the whole sigma catalog of precursors in their 12C form. You can feed those and look for incorporation in … would grow up our bacteria on 13C methane or methanol, feed 12C methionine, and we were able to pull out the quorum …

… the Molecular Foundry, the project needs to be scoped for 12 months or less. We can help you scope that part of the proposal. Also, once awarded, users have 12 months before they need to activate their project. … end of an active proposal in order to continue access in 12-month increments.  At the JGI, a typical proposal is …

… in Yu et al, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 1253–1262, 70:3 ALISON TAKEMURA: And so did you succeed in … Nature  Biotechnology . 2020 Nov 9. doi: 10.1038/s41587-020-0718-6) DAN UDWARY: Yeah, I think that might be a good … Microbiomes” paper is here . Read the associated JGI news release here . Software we discussed, used for genome …

… there a way to do that? DAN UDWARY: Well, so there’s good news and bad news on that. So one of the things that we’re … happening. And so we should have somewhere around 10, 11, 12 million BGCs in the database on the release, and that’s …

… right? BEN: Yeah, yeah. Well, we are at [10 to the] minus 12 [Molar concentration]- is sufficient to kill cells. So … So I wanted to ask you also about – because you were in the news recently – TSRI has acquired the Pfizer strain …

… as well as a unique opportunity to complete a California K-12 science or math teaching credential as an undergraduate …

… never forced it on me, but we always had these scientific news magazines lying around at home. And I would just pick … takes about 10 years. Costs are in the range of $100 to $120 million to do that.  DAN: OK. So about the same amount …

… plants and bringing them back is not your jam, the good news is there’s this amazing resource that can be provided …